Last updated: March 2025

Understanding Osteoarthritis: Causes, Symptoms, and Treatment Options

Article Highlights

Osteoarthritis is a degenerative joint disease that affects millions of people worldwide, leading to pain, stiffness, and decreased mobility. This condition occurs when the cartilage that cushions the joints wears down over time, resulting in inflammation and discomfort. This guide provides an insight of the causes, symptoms, and effective treatment options for osteoarthritis, preventions as well as complication that can occur.

A Sneak Peek at What's Inside





What is Osteoarthritis (OA)?

Osteoarthritis (OA) is the most common form of arthritis, affecting millions globally. It is a degenerative joint disease that occurs when the protective cartilage that cushions the ends of the bones gradually wears down over time. It is the most common type of arthritis and is more common in older people. OA primarily affects the joints in the hands, knees, hips, and spine. While the symptoms can often be managed, the damage to the joints is irreversible. Active lifestyles, healthy weight management, and certain treatments may help slow the disease's progression and improve pain and joint function.

Incidence of Chronic Kidney Disease

Osteoarthritis affects more than 32.5 million adults in the United States alone. It is more prevalent in older adults, typically presenting symptoms in individuals over the age of 50. The disorder can affect anyone, but it is particularly common in women, who are more likely to develop OA than men.


Risk factors for Osteoarthritis

Several risk factors increase the likelihood of developing osteoarthritis:

  • Age: Risk increases with age, particularly in those over 50.
  • Joint injuries: Previous fractures or tears can expedite OA onset.
  • Repetitive stress: Jobs or activities that involve repetitive joint use heighten risk.
  • Obesity: Excess weight places additional pressure on joints.
  • Musculoskeletal abnormalities: Misalignment of bones or joints can speed up OA progression.
  • Weak muscles: Insufficient muscle support can lead to poor alignment and increased stress on joints.
  • Gender: Women are more prone to developing OA than men.
  • Environmental factors: Factors such as occupation, activity level, and previous joint injuries also play a role.

Causes of Osteoarthritis

Osteoarthritis is caused by the breakdown of cartilage and other joint tissues. This degeneration can occur due to various factors, including:

  • Aging:The risk of developing OA increases with age.
  • Obesity:Excess weight adds stress on joints and promotes inflammation through fat cells.
  • Joint injury:Prior injuries or surgeries can lead to OA.
  • Overuse:Repeated joint movements in occupations or sports can accelerate cartilage wear.
  • Genetics:A family history of osteoarthritis increases susceptibility.
  • Structural abnormalities:Improperly formed joints can contribute to OA development.


Pathophysiology of Osteoarthritis

The precise triggers for OA remain unknown, but the disease impacts all joint structures, including cartilage, tendons, ligaments, and bone. As OA develops, cartilage becomes damaged and wears away, leading to symptoms like pain, swelling, and limited motion. Changes in the joint can result in the formation of bone spurs and alterations in joint shape.

The pathological process involves:

  • Surface fibrillation and irregularities in articular cartilage.
  • Damage to the collagen matrix, leading to chondrocyte apoptosis.
  • Synovial inflammation and hypertrophy, though these are secondary to the primary degenerative process.



Signs & Symptoms of Osteoarthritis

Symptoms of osteoarthritis typically begin gradually and may include:

  • Joint pain - Often exacerbated by movement and relieved by rest.
  • Stiffness - Usually lasting less than 30 minutes, particularly noticeable in the morning or after periods of inactivity.
  • Swelling - In and around the joint, especially after prolonged use.
  • Reduced mobility - Difficulty moving the affected joint.
  • Joint instability - A sensation of looseness in the joint.

Symptoms of osteoarthritis can vary significantly among individuals, with some experiencing mild discomfort while others may face substantial pain and disability.


Diagnostic Test & Investigations

Diagnosing osteoarthritis involves a combination of medical history, physical examination, and imaging studies:

  • Medical history: Review of symptoms and their impact on daily activities.
  • Physical examination: Assessment of joint function and any visible swelling or tenderness.
  • X-rays: To identify joint or bone damage.
  • MRI: Provides a detailed view of cartilage and other joint structures.
  • Joint aspiration: Extracting fluid from the joint to check for infection or crystals.


Treatment of Osteoarthritis

While there is no cure for osteoarthritis, several treatment options can help manage symptoms:

Analgesics:Pain relievers like acetaminophen and opioids.

NSAIDs:Nonsteroidal anti-inflammatory drugs to reduce pain and inflammation (e.g., ibuprofen, naproxen).

Corticosteroids:Prescription anti-inflammatory medications for severe cases.

Counter-irritants:Topical treatments that provide temporary pain relief.

Physical therapy:Strengthening exercises and flexibility training can improve joint function.

Assistive devices:Canes, braces, or shoe inserts may alleviate pressure on joints.

Surgery:In severe cases, joints may be surgically fused or replaced.

Nursing Management of Osteoarthritis

The subsequent measures are essential for effectively caring for patients with Osteoarthritis

  • Check and monitor vitals
  • Provide rest for your patient
  • Avoid activities that precipitate pain
  • Protect and provide rest for the affected joint
  • Ensure that patient uses correct posture and body mechanics
  • Apply heat as when and necessary (as prescribed)
  • Serve foods rich in vitamins and correct proportions of necessary food nutrients
  • Make sure dieting does not result in over weight
  • Give adequate fluids
  • Monitor patient to take his drugs (anti - inflammatory drugs) and also observe for any side effects of the drugs
  • Monitor patient's weight
  • Ensure patient to take the prescribed analgesics for pain.
  • Keep patient active for increased physical mobility
  • Instruct patient to avoid flexion and adduction deformities
  • Use graded and isometric exercise to improve muscle strength at the affected joints.

Complications of Osteoarthritis

Complications of osteoarthritis can include:

  • Chronic pain
  • Joint malalignment
  • Decreased mobility
  • Weight gain resulting from reduced physical activity.
  • Hemarthrosis, or bleeding near the joints
  • Psychological effects - increased risk of anxiety and depression.
  • Falls
  • Difficulty ambulation
  • Joint malalignment
  • Osteonecrosis, or bone death

Other possible complications may include osteonecrosis, erosion of ligaments and tendons, and stress fractures.

Preventions of Osteoarthritis

Preventive measures can help slow the progression of osteoarthritis and maintain joint health:

  • Maintain a healthy weight - Reducing stress on joints through balanced nutrition and regular exercise.
  • Control blood sugar - Managing diabetesto prevent cartilage stiffness.
  • Exercise regularly - Engage in low-impact activities to maintain joint flexibility.
  • Protect joints - Use proper techniques and equipment when exercising or playing sports.
  • Stress management - Employ relaxation techniques to reduce overall stress levels.
  • Healthy lifestyle choices - Avoid smoking, limit alcohol consumption, and ensure adequate sleep.